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CNS Clinical Nurse Specialist

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CNS exam Dumps Source : Clinical Nurse Specialist

Test Code : CNS
Test Name : Clinical Nurse Specialist
Vendor Name : Medical
Q&A : 20 Real Questions

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Medical Clinical Nurse Specialist

highly specialist medical Psychologist | killexams.com Real Questions and Pass4sure dumps

The details
  • Speciality: Psychologist
  • Grade: clinical Psychologist
  • profits: £30 - £32 per hour
  • vicinity: London
  • start Date: Required ASAP
  • length: temporary
  • Reference No: CB6973
  • Job Shortlist observe for this job

    Mediplacements intellectual fitness are at present recruiting for a totally professional medical Psychologist in London.Job Reference: CB6973Highly specialist clinical PsychologistBand 8aLocation: LondonStart date: immediate startMinimum of 3 months4 days per week* ought to have event working with got mind injuries *

    we are company believers in featuring not only the appropriate job, however also making certain that proficient people are paid for this reason for his or her competencies. Our pay costs are therefore very captivating and are supplemented via various further benefits. Which encompass:

    -A dedicated one to 1 service-quick track registration manner-remarkable prices of pay-assistance with shuttle and inexpensive accommodation-Weekly pay - on time, anytime-access to unique NHS and private sector jobs-No Registration fee!-Reimbursed DBS exams-Free online training purchasable

    now not attainable for this position Why not suggest a friend or colleague and earn a £250 referral bonus on successful placement (phrases and qualifying length observe).

    If this sounds like the next job for then you please contact Csaba on 0207 613 6815!


    what is the difference Between a scientific Nurse professional & a Nurse Practitioner? | killexams.com Real Questions and Pass4sure dumps

    Job responsibilities of nurses

    Job duties of nurses

    clinical nurse specialists and nurse practitioners are both advanced observe nurses who every so often work in lots of of the identical forms of fitness care amenities. both require an MSN, or master of science in nursing, diploma and each can also contain direct affected person care. despite the fact, there are a few huge changes between both professions.


    SC's proposed medical marijuana legislation: a better look | killexams.com Real Questions and Pass4sure dumps

    COLUMBIA, S.C. — South Carolina is proposing legalizing clinical marijuana to aid people who undergo from definite continual illnesses and ache. 

    So, what would the bill basically do? And who would improvement from it? 

    Let's take a deeper appear on the SC Compassionate Care Act, invoice S.366 within the SC Senate, added by using Senators Tom Davis (R-forty six), Brad Hutto (D-40), Paul Campbell (R-44), Marlon Kimpson (D-forty two), Darrell Jackson (D-21), Mia McLeod (D-22), and M.B. Matthews (D-forty five). 

    Davis says the bill is the most strictly regulated and socially conservative clinical marijuana bill within the nation and reflects the subculture of South Carolinians. The invoice has gone through four years of subcommittee processes with a whole lot of hours of testimony and legislative opinions included into the latest edition. 

    The senators hope that Gov. Henry McMaster will signal the invoice into legislation in 2019.

    What the bill would permit
  • up to 2 oz. of scientific hashish within the styles of vaporized flower or oil, gel caps, suppositories, patches, edibles or topical lotions.
  • Smoking cannabis would no longer be allowed. it would be illegal for a cardholder to smoke hashish or use a device to facilitate the smoking of hashish. A violation of this subsection is punishable by way of a civil first-class of up to $a hundred and fifty.
  • Distribution of medical marijuana to someone for leisure use could be unlawful, with fines as much as $5,000 and/or up to 5 years in reformatory.
  • Who it will cover

    There should be a strict latitude of situations for the approval of use of clinical marijuana, and no need might be allowed without healthcare professional supervision and authorization.

    in keeping with the invoice: stories posted due to the fact that the 1999 Institute of drugs document proceed to show the therapeutic cost of hashish in treating a wide selection of debilitating clinical circumstances. These include aid of the neuropathic ache that frequently fails to respond to typical remedies; a discount in patients' reliance on opiate-based painkillers; decreased signs and even complete remission from Crohn's disease; and reduction of severe nausea, thereby expanding the probabilities of patients carrying on with existence-saving medicine regimens.

    'Debilitating scientific situation' capacity one or more of the following:

  • melanoma currently requiring remedy
  • numerous sclerosis
  • a neurological ailment or sickness
  • glaucoma
  • post-anxious stress disorder (PTSD)
  • Crohn's ailment
  • ulcerative colitis
  • cachexia or wasting syndrome
  • sickle mobile anemia
  • severe or persistent nausea in someone who isn't pregnant and that's regarding end of life or hospice care, or the particular person is bedridden or domestic sure as a result of the condition
  • a continual scientific circumstance causing extreme and chronic muscle spasms
  • or any persistent or debilitating ailment or medical condition for which an opioid is presently or may well be prescribed via a physician in accordance with often permitted specifications of care.
  • sufferers in quest of scientific marijuana have to have written certification. 

    within the invoice, 'written certification' skill a document signed by a physician, stating that the affected person has been diagnosed with a debilitating medical situation and will improvement from the use of clinical cannabis. The certification may be made most effective throughout a bona fide physician-affected person relationship, must specify the qualifying affected person's debilitating clinical condition, and have to be up to date yearly for each qualifying patient by means of the certifying doctor. If the qualifying patient is expected to recuperate from the debilitating scientific situation within a 12 months of the written certification, no longer together with if the patient may additionally go into remission due to clinical hashish medicine, or the qualifying affected person is not anticipated to advantage from clinical hashish for a complete year, the written certification shall specify that fact.

    sufferers may be issued an identification card with the prescription for medical marijuana.

    becoming scientific marijuana

    The invoice states "all cultivation, harvesting, processing, and packaging of hashish must take area in a relaxed facility at a actual address supplied to the branch and SLED all over the processing facility or cultivation core's registration process. The comfortable facility may be accessed only by way of agents of the scientific cannabis establishment, legislation enforcement, emergency personnel, and adults who are twenty-one years of age and older who are accompanied with the aid of clinical cannabis institution agents. enterprises are field to random inspections by way of SLED.

    "To evade diversion and offer protection to public safety, the DHEC shall require the use of a single true-time, seed-to-sale monitoring system used by using all scientific cannabis companies and the branch that complies with medical health insurance Portability and Accountability Act (HIPAA) instructions, is hosted on a platform that enables for dynamic allocation of materials, offers facts redundancy, and is in a position to recovering from natural disasters inside hours." 

    give chain auditing techniques like this are a edition of Blockchain expertise that permits the monitoring of items via all phases of creation from increase to distribution, together with earnings, recalls and theft.

    under the bill, DHEC shall require that the gadget be able to:

  • tracking all plants, products, applications, sufferers, waste, transfers, conversions, applications, sales, and returns, and all with interesting identification numbers;
  • tracking lot and batch assistance throughout the total chain of custody except the point of sale to a cardholder;
  • tracking all product, conversions, and derivatives during the complete seed-to-sale chain of custody;
  • tracking plant, batch, and product destruction;
  • monitoring transportation of product;
  • performing complete batch recollect tracking capabilities that need to be capable of naturally determine the entire following details relating to the particular batch subject to the do not forget: all bought product; product attainable for sale (product that is in entire inventory, but now not offered); product that's in the transfer method; work in development (product it's being transformed); and raw material (product that is within the submit-harvest process, reminiscent of drying, trimming, and curing);
  • reporting and tracking loss, theft, or diversion of product containing hashish;
  • reporting and monitoring all inventory discrepancies to the branch;
  • reporting and tracking all revenue and refunds to the department;
  • receiving trying out results electronically from independent testing laboratories by way of a secure utility program interface (API) into the seed-to-sale monitoring device, and directly attaching the testing consequences to the supply batch and/or sample;
  • restricting the altering of look at various results with the aid of the operator;
  • offering the department with precise-time access to the database;
  • proposing actual-time analytics to the branch concerning key efficiency warning signs including, however not restricted to: complete each day earnings; total plants in creation; total plants destroyed; and complete stock changes
  • presenting different assistance precise by the department.
  • doling out scientific marijuana

    each dispensary should contract with or employ as a minimum one pharmacist, healthcare professional assistant, nurse practitioner, or medical nurse specialist, who has accomplished a branch-authorised medical cannabis carrying on with education route. The pharmacist, surgeon assistant, nurse practitioner, or medical nurse specialist need to be moderately accessible to advise and educate patients, in adult or by means of telemedicine. A pharmacist, surgeon assistant, nurse practitioner, or medical nurse specialist may contract with dissimilar dispensaries.

    Funding the scientific marijuana software

    A South Carolina clinical hashish software Fund might be established to make certain the provision of cash necessary to perform the DHEC's responsibilities beneath this text. All monies collected pursuant to this article must be deposited into the fund. The cash ought to be used completely for the direct and indirect charges linked to the implementation, administration, and enforcement of this text.

    Revenues generated in extra of the amount essential to enforce and enforce this act can be distributed every three months as follows: (a) fifty % to the South Carolina law Enforcement Division; (b) twenty-5 p.c to the South Carolina branch of training; and (c) twenty-five % to the state time-honored Fund.

    All revenue of medical hashish are field to a six percent excise tax at the point of sale.

    Oversight

    A 9-member clinical hashish Advisory Board may be created that can be required to meet at the least twice a yr to be able to evaluate petitions to add qualifying conditions, consult with consultants in South Carolina and different states with medical hashish classes about ongoing analysis within the container, and, if fundamental, hang public hearings earlier than vote casting on whether so as to add new qualifying circumstances.

    The board contributors would serve four 12 months phrases and the board need to be constituted of one appointment from each and every of the following:

  • the executive of State law Enforcement Division or his designee;
  • The director of the branch or his designee;
  • Two licensed clinical doctors approved to practice in this State, appointed by means of the Governor and tested by means of the Senate;
  • One licensed medical professional of osteopathic medicine approved to observe in this State, appointment through the Governor and established by means of the Senate;
  • One licensed pharmacist approved to observe during this State, appointed by way of the Governor and demonstrated by using the Senate;
  • One cardholder, appointed by way of the Governor and tested by way of the Senate;
  • One representative of a registered clinical hashish institution, appointed with the aid of the Governor and validated with the aid of the Senate;
  • One consultant from a municipality of this State; appointed via the Governor and verified by way of the Senate

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    Clinical Nurse Specialist

    Pass 4 sure CNS dumps | Killexams.com CNS real questions | [HOSTED-SITE]

    'Outside-of-the-box nurse' helps patients navigate their treatment | killexams.com real questions and Pass4sure dumps

    MOLINE — Her job lets her do what many of her colleagues wish they had time to do.

    Cassie Burns, 33, of Milan, works as a clinical nurse specialist at UnityPoint Health-Trinity Moline.

    "I'm a nurse navigator who works with breast-cancer patients and with people having high risks for cancer," she said.

    Beginning with a patient's first day of treatment, Burns goes with the patient to all appointments, even if they are with people who aren't affiliated with Trinity, she said.

    It gives Burns the chance to make much more of a personal connection, which is something most nurses wish they had time for, she said.

    She gives patients all the information she can give them about what threatens their health.

    Previously, Burns had been an oncology nurse for 11 years, starting right after graduating from Black Hawk College. She accepted her navigator position five years ago.

    Navigators are a relatively new position that was created within the past 10 years or so, she said.

    "Most hospitals find that it improves quality," Burns said. "It's an outside-of-the-box nurse. It's what you make of it. It's making sure people have what they need and that all the physicians are on the same page."

    Burns said she had thought about becoming a pediatric nurse, but she switched to health-care nursing after learning more about it.

    "It's different to care for these patients," Burns said. "They have different attitudes toward the process, and lots of needs that I get to help."

    "I love this job," she said. "I really like to come to work. I enjoy it, and don't dread it all. I really don't know what I would do without it."

    Her work schedule allows her to do a lot of community outreach, too.

    "I will do a lot of education about breast-cancer screening," she said.

    She has spoken at programs sponsored by churches and at other events with attendance ranging from five to 20 people. She's available to speak to any size group; call her at 309-779-5080 to set something up.

    Burns also serves as an education ambassador for a national nonprofit organization named Bright Pink, joining it about four years ago.


    “We should study that!”: How a nurse-scientist found her passion | killexams.com real questions and Pass4sure dumps

    “We should study that!”: How a nurse-scientist found her passion Nurse-scientist Kimberly Pyke-Grimm draws on her clinical experience when studying how teens, young adults and families make decisions about cancer care. Author Erin DigitalePublished on February 20, 2019February 20, 2019

    My favorite moment in the Harry Potter series is the sorting hat scene from Harry Potter and the Sorcerer's Stone, when all the new Hogwarts students are magically sorted into their houses. After a few moments of sitting in suspense with the chatty sorting hat on his head, Harry ends up in Gryffindor with his friends Ron and Hermione. Phew!

    Because I get to interview people who love their jobs, I like to ask how they "got sorted" into the work they do. I received an especially interesting answer during a recent conversation with Kimberly Pyke-Grimm, PhD, a nurse-scientist at Lucile Packard Children's Hospital Stanford.

    My story explains:

    When Pyke-Grimm began working in pediatric oncology, she was struck by the painful uncertainties families faced as they made treatment choices for their children. Parents might agonize over whether to enroll a young child in a clinical trial, grapple with the choice between different cancer treatments or battle complicated feelings while deciding on end-of-life care.

    'As a bedside nurse, I really bore witness to them struggling to make some of those decisions,' Pyke-Grimm said.

    ...Pyke-Grimm... earned a master’s degree in nursing, an experience that hooked her on nursing research. When [she and her husband] moved to Winnipeg, Canada, in 1991, Pyke-Grimm collaborated with Lesley Degner, PhD, a professor of nursing at the University of Manitoba. Degner studied decision-making in adults with cancer. Together, she and Pyke-Grimm extended these investigations to parents of young kids with cancer.

    'I was so very fortunate, working with Lesley,' Pyke-Grimm said. “I felt like, ‘This is my home: decision-making research.'

    Today, Pyke-Grimm has extended her research to ask how teenagers and young adults with cancer make decisions about their care. She spends 40 percent of her time on research and 60 percent on clinical care, and continues to bring a nurse's perspective to her research:

    Almost every day that I work as a clinical nurse specialist, I think ‘We should study that!’ or ‘Why is it we’re doing it this way?’

    Photo by Steve Fisch

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  • Category Cancer Careers Patient care Pediatrics Tags cancer301 nursing2 pediatrics340 Related posts Category: Education A nurse becomes a doctorA nurse becomes a doctor Author Jacqueline GenovesePublished on September 14, 2015March 19, 2018 Category: Careers New postdoctoral fellowship will allow nurse-scientists to conduct palliative care researchNew postdoctoral fellowship will allow nurse-scientists to conduct palliative care research Stanford Medicine is introducing a new postdoctoral fellowship for nurse-scientists in palliative care. The program begins in the fall. Author Lindsey BakerPublished on March 21, 2018March 21, 2018 Popular posts Category: Neuroscience Can a brain parasite found in cats influence soccer talent?Can a brain parasite found in cats influence soccer talent? Author Lia SteakleyPublished on July 2, 2010February 28, 2019 Category: Aging Commonly used drugs can affect PSA measurementCommonly used drugs can affect PSA measurement Author Bruce GoldmanPublished on August 11, 2010February 22, 2019

    Ipsen to Present New Data on Enhancement of Patient Care at the 16th European Neuroendocrine Tumor Society (ENETS) Annual Conference | killexams.com real questions and Pass4sure dumps

    Regulatory News:

    Ipsen (Euronext: IPN; ADR: IPSEY) today announced that they are looking forward to revealing 17 presentations that detail their research into neuroendocrine tumors (NETs) at the 16th European Neuroendocrine Tumor Society (ENETS) Annual Conference, which is taking place in Barcelona, Spain between 6th-8th March 2019.

    One of the key presentations, titled (Abstract #H14) ‘Development of a new and improved delivery system for lanreotide autogel/depot to further enhance care for patients with NETs and acromegaly’, reports results from five separate, but complementary studies designed to inform and test enhancements to the existing Somatuline® Autogel® (lanreotide) pre-filled syringe.1

    Input from patients and their caregivers, as well as nurses and other healthcare professionals, was used to design a new pre-filled syringe1 that was submitted to the European Union as a type II variation via a work-sharing procedure with HPRA (Ireland) as the reference country. Following a positive outcome of the work-sharing procedure, each member state would consider a national approval. Notable new features are modified ergonomics and handling, a needle shield removal system, an injection process with plunger support and heightened ease of use.1

    "It is our mission to ensure patients continue to receive optimized care as they navigate the challenges of living with NETs and acromegaly,” said Sotirios Stergiopoulos, Chief Medical Officer at Ipsen. "The data we are sharing at this year’s ENETS conference underscores our commitment to understanding the patient experience and to supporting a multidisciplinary treatment approach to make treatment administration as simple as possible whether in hospital or at home.”

    "For nurses and other healthcare practitioners treating patients with NETs or acromegaly, the value of innovation across the entire treatment landscape supports our ability to provide the best care for our patients,” said Daphne T Adelman, Clinical Nurse Specialist from Northwestern University in Chicago, U.S. and one of the authors of the study. "As a nurse who administers treatments to patients often, efficient pre-filled syringes allow me to save time and focus on patients and their needs.”

    Also, being highlighted are results from:

    (Abstract #H18) Tumour growth rate (TGR) to monitor growth/predict response to lanreotide autogel (LAN) use before, during and after peptide receptor radionuclide therapy (PRRT) in advanced gastroenteropancreatic neuroendocrine tumors (GEP-NETs): data from PRELUDE

    This abstract has been selected for a poster walk during ENETS’ scientific program and will report effectiveness data and post-hoc analyses of tumor growth rate (TGR) as a measure of response to LAN–PRRT (lanreotide autogel – peptide receptor radionuclide therapy).

    (Abstract #M03) ATLANT, phase 2 study combination trial between long acting somatostatin analogue (SSA) lanreotide (LAN) and temozolomide (TMZ) in progressive thoracic (lung / thymus) well differentiated NET (carcinoid) (TNETS).

    (Abstract #F22) Exploratory assessment of the clinical value of baseline (BL) circulating tumour cells (CTC) to predict symptomatic response in pts with functioning midgut neuroendocrine tumours (NETs) receiving lanreotide autogel (LAN): CALM-NET study results

    In addition to these posters, Ipsen will share data from the following 13 company sponsored or supported studies and literature reviews:

    (Abstract #H17) Safety and Efficacy of 14-Day Dosing Interval of Lanreotide Autogel/Depot (LAN) For Patients With Pancreatic or Midgut Neuroendocrine Tumours (NETs) Progressing on LAN Every 28 Days: The Prospective, Open-label, International, Phase 2 CLARINET FORTE Study

    (Abstract #P04) Lanreotide autogel 120mg (LAN) in patients (pts) with locally advanced or metastatic gastroenteropancreatic neuroendocrine tumours (GEP-NETs): prospective observational NETways study

    (Abstract #D13) Satisfaction Survey of Administration Modes for Long-Acting (LA) Somatostatin Analog (SSA) Therapy in Patients (pts) with Neuroendocrine Tumuors (NETs): Results of Cognitive Interviews With Patients and Nurses

    (Abstract #J15) The Effect of Carcinoid Syndrome Diarrhea (CSD) Interventions on Patient Experience Outcomes: a Systematic Literature Review (SLR)

    (Abstract #J08) Differential Diagnosis (DDx) of Carcinoid Syndrome Diarrhea (CSD): a Systematic Literature Review (SLR)

    (Abstract #H25) Evaluation of the use of resources and costs associated with Uncontrolled or Controlled Carcinoid Syndrome (CS) in patients (pts) with Neuroendocrine Tumours (NETs) in Spain: RECOSY study

    (Abstract #F10) Relationship between biomarkers and number of liver metastases at the time of diagnosis of small intestinal neuroendocrine tumors

    (Abstract #A11) Evaluation of gene expression changes associated with response to somatostatin analogues (SSAs) in gastrointestinal (GI) neuroendocrine tumors (NETs)

    (Abstract #J07) Long-term Treatment with Telotristat Ethyl (TE) in Patients with Carcinoid Syndrome (CS) Symptoms: Results from TELEPATH Study

    (Abstract #P05) TELEFIRST: A randomized phase III clinical trial of Lanreotide (LAN) combined with Telotristat ethyl (TE) or placebo (PBO) for the First-line treatment in patients (pts) with advanced well-differentiated (wd) small intestinal neuroendocrine tumours (siNET) with highly-functioning carcinoid syndrome (CS)

    (Abstract #K30) OPS-C-001: A Phase I/II Study To Investigate Safety, Tolerability, Biodistribution, Dosimetry and Preliminary Efficacy of 177Lu-OPS201 for the Therapy of Somatostatin Receptor (SSTR)-Positive Neuroendocrine Tumours (NETs)

    (Abstract #P08) Study to evaluate the optimal dose of 68Ga-OPS202 as a PET imaging agent in patients with GEP-NETs

    (Abstract #D33) Establishment of a NET data base in a German tertiary referral center; preliminary results

    About SOMATULINE®2

    Somatuline® Autogel® is made of the active substance lanreotide, which is a long-acting somatostatin analogue that inhibits the secretion of growth hormone and certain hormones secreted by the digestive system. The main indications of Somatuline® and Somatuline® Autogel® are:2

  • The treatment of individuals with acromegaly when the circulating levels of Growth Hormone (GH) and/or Insulin-like Growth Factor-1 (IGF-1) remain abnormal after surgery and/or radiotherapy, or in patients who otherwise require medical treatment.
  • The treatment of grade 1 and a subset of grade 2 (Ki-67 index up to 10%) gastroenteropancreatic neuroendocrine tumors (GEP-NETs) of midgut, pancreatic or unknown origin where hindgut sites of origin have been excluded, in adult patients with unresectable locally advanced or metastatic disease.
  • The treatment of symptoms associated with neuroendocrine (particularly carcinoid) tumors.
  • Important Safety Information

  • The detailed recommendations for the use of Somatuline Autogel are described in the Summary of Product Characteristics (SmPC), available here.
  • About XERMELO®3

    Xermelo® is a novel, orally administered, inhibitor of the enzyme tryptophan hydroxylase (TPH). Through inhibition of TPH, the rate-limiting step in the synthesis of serotonin, Xermelo® was designed to reduce the production of serotonin within neuroendocrine tumors.

    Xermelo® (telotristat ethyl) is commercialized by Ipsen in all territories excluding the United States and Japan, where Lexicon retains the rights. Lexicon has approval for Xermelo® in the U.S. as a first and only orally administered therapy for the treatment of carcinoid syndrome diarrhea in combination with somatostatin analog (SSA) therapy in adults inadequately controlled by SSA therapy.

    Xermelo® is approved in Europe for the treatment of carcinoid syndrome diarrhea in patients inadequately controlled by somatostatin analogue therapy.

    Important Safety Information

  • The detailed recommendations for the use of Xermelo are described in the Summary of Product Characteristics (SmPC), available here.
  • References1 Data on File. ENETS ‘192 Somatuline Autogel SmPC. November 20183 Xermelo SmPC. January 2019

    About Ipsen

    Ipsen is a global specialty-driven biopharmaceutical group focused on innovation and Specialty Care. The group develops and commercializes innovative medicines in three key therapeutic areas - Oncology, Neuroscience and Rare Diseases. Its commitment to Oncology is exemplified through its growing portfolio of key therapies for prostate cancer, neuroendocrine tumors, renal cell carcinoma and pancreatic cancer. Ipsen also has a well-established Consumer Healthcare business. With total sales over €2.2billion in 2018, Ipsen sells more than 20 drugs in over 115 countries, with a direct commercial presence in more than 30 countries. Ipsen's R&D is focused on its innovative and differentiated technological platforms located in the heart of the leading biotechnological and life sciences hubs (Paris-Saclay, France; Oxford, UK; Cambridge, US). The Group has about 5,700 employees worldwide. Ipsen is listed in Paris (Euronext: IPN) and in the United States through a Sponsored Level I American Depositary Receipt program (ADR: IPSEY). For more information on Ipsen, visit www.ipsen.com.

    Forward Looking Statement

    The forward-looking statements, objectives and targets contained herein are based on the Group’s management strategy, current views and assumptions. Such statements involve known and unknown risks and uncertainties that may cause actual results, performance or events to differ materially from those anticipated herein. All of the above risks could affect the Group’s future ability to achieve its financial targets, which were set assuming reasonable macroeconomic conditions based on the information available today. Use of the words "believes", "anticipates" and "expects" and similar expressions are intended to identify forward-looking statements, including the Group’s expectations regarding future events, including regulatory filings and determinations. Moreover, the targets described in this document were prepared without taking into account external growth assumptions and potential future acquisitions, which may alter these parameters. These objectives are based on data and assumptions regarded as reasonable by the Group. These targets depend on conditions or facts likely to happen in the future, and not exclusively on historical data. Actual results may depart significantly from these targets given the occurrence of certain risks and uncertainties, notably the fact that a promising product in early development phase or clinical trial may end up never being launched on the market or reaching its commercial targets, notably for regulatory or competition reasons. The Group must face or might face competition from generic products that might translate into a loss of market share. Furthermore, the Research and Development process involves several stages each of which involves the substantial risk that the Group may fail to achieve its objectives and be forced to abandon its efforts with regards to a product in which it has invested significant sums. Therefore, the Group cannot be certain that favourable results obtained during pre-clinical trials will be confirmed subsequently during clinical trials, or that the results of clinical trials will be sufficient to demonstrate the safe and effective nature of the product concerned. There can be no guarantees a product will receive the necessary regulatory approvals or that the product will prove to be commercially successful. If underlying assumptions prove inaccurate or risks or uncertainties materialize, actual results may differ materially from those set forth in the forward-looking statements. Other risks and uncertainties include but are not limited to, general industry conditions and competition; general economic factors, including interest rate and currency exchange rate fluctuations; the impact of pharmaceutical industry regulation and health care legislation; global trends toward health care cost containment; technological advances, new products and patents attained by competitors; challenges inherent in new product development, including obtaining regulatory approval; the Group's ability to accurately predict future market conditions; manufacturing difficulties or delays; financial instability of international economies and sovereign risk; dependence on the effectiveness of the Group’s patents and other protections for innovative products; and the exposure to litigation, including patent litigation, and/or regulatory actions. The Group also depends on third parties to develop and market some of its products which could potentially generate substantial royalties; these partners could behave in such ways which could cause damage to the Group’s activities and financial results. The Group cannot be certain that its partners will fulfil their obligations. It might be unable to obtain any benefit from those agreements. A default by any of the Group’s partners could generate lower revenues than expected. Such situations could have a negative impact on the Group’s business, financial position or performance. The Group expressly disclaims any obligation or undertaking to update or revise any forward-looking statements, targets or estimates contained in this press release to reflect any change in events, conditions, assumptions or circumstances on which any such statements are based, unless so required by applicable law. The Group’s business is subject to the risk factors outlined in its registration documents filed with the French Autorité des Marchés Financiers. The risks and uncertainties set out are not exhaustive and the reader is advised to refer to the Group’s 2017 Registration Document available on its website (www.ipsen.com).



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